Antiemetic and Myeloprotective Effects of Rhus verniciflua Stoke in a Cisplatin-Induced Rat Model
Table 1
Hematologic parameters and organ weights.
Parameters
Normal
Control
RVX 25
RVX 50
RVX 100
Met 25
WBC (k/μL)
5.44 ± 1.19
3.12 ± 0.45###
3.20 ± 0.61
3.87 ± 0.63
5.59 ± 1.62
4.14 ± 0.28
Neutrophils (k/μL)
0.52 ± 0.12
0.68 ± 0.24
0.62 ± 0.25
0.73 ± 0.18
1.01 ± 0.33
0.93 ± 0.60
Lymphocytes (k/μL)
4.73 ± 1.06
2.27 ± 0.43###
2.46 ± 0.48
2.97 ± 0.44
4.33 ± 1.23
3.06 ± 0.40
Monocytes (k/μL)
0.03 ± 0.02
0.04 ± 0.01
0.04 ± 0.04
0.05 ± 0.02
0.13 ± 0.06
0.08 ± 0.03
Basophil (k/μL)
0.01 ± 0.00
0.03 ± 0.02#
0.02 ± 0.01
0.03 ± 0.01
0.03 ± 0.01
0.03 ± 0.01
Eosinophil (k/μL)
0.05 ± 0.05
0.08 ± 0.06#
0.03 ± 0.02
0.09 ± 0.03
0.08 ± 0.04
0.05 ± 0.02
RBC (m/μL)
7.58 ± 0.37
7.09 ± 0.20#
6.89 ± 0.67
7.31 ± 0.27
7.31 ± 0.10
7.16 ± 0.23
Hemoglobin (g/dL)
14.68 ± 1.17
14.45 ± 0.71
14.40 ± 1.60
14.75 ± 0.55
15.35 ± 0.73
14.68 ± 0.56
Platelet (k/μL)
1091.50 ± 31.89
907.75 ± 173.30
661.00 ± 302.11
1191.75 ± 330.96
1189.50 ± 46.26
1138.75 ± 139.90
Thymus weight (g) (Relative%)
0.67 ± 0.11
0.34 ± 0.08###
0.34 ± 0.05
0.46 ± 0.06
0.50 ± 0.03
0.48 ± 0.06
(0.24 ± 0.04)
(0.15 ± 0.04###)
(0.17 ± 0.02)
(0.20 ± 0.02)
(0.22 ± 0.01)
(0.21 ± 0.04)
Spleen weight (g) (Relative%)
0.81 ± 0.10
0.50 ± 0.03###
0.47 ± 0.02
0.59 ± 0.10
0.60 ± 0.05
0.58 ± 0.07
(0.31 ± 0.04)
(0.24 ± 0.02###)
(0.22 ± 0.02)
(0.24 ± 0.01)
(0.27 ± 0.02)
(0.25 ± 0.02)
Data are expressed as the mean SD (). and , compared with normal group; , , and , compared with control group. WBC: white blood cell; RBC: red blood cell.
