New Contributions to Asarum Powder on Immunology Related Toxicity Effects in Lung

Figure 3

The effect of Asarum on the protein level changes in lung tissues of rats. Western blotting was performed to detect the protein expression of Ampk, Bcl2, Caspase 3, Il1, Il20, Matriptase2, Nfκbp65, Nptx2, and Rag2 in lungs of rats after intragastric administration with/without Asarum powders. The results showed that the expressions of the Ampk, Caspase 3, Il1, Il20, Matriptase2, Nfκbp65, and Rag2 were upregulated after intragastric administration with Asarum powders, the expression of Bcl2 was downregulated. The expression of Nptx2 was meaningless. The results may be induced by the toxicity of Asarum on lung in rats. The data were the means ± standard error of at least three independent experiments. All comparisons were performed with WPS office (kingsoft, China), utilizing unpaired t-test with Welch’s correction. Statistical significance was marked as※ while p<0.05. ※represent the significant difference between the Asarum group and control group (p<0.05).

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