Evidence-Based Complementary and Alternative Medicine / 2018 / Article / Tab 3 / Review Article
The Efficacy and Safety of Acupuncture for the Treatment of Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis Table 3 Adverse events in included studies.
Study (reference) Sample size (E/C) Adverse events J. G. Sun and X. R. Sun 2014 [35 ] 42/42 None Wong 2008 [40 ] 18/18 E: 1 (worsening of sleep pattern; sleeping late at night), 1 (worsening of hyperactivity and ritualistic behavior) Parents thought that the negative changes were minor and did not affect the participant’s functioning Wong and Chen 2010 [41 ] 30/25 E: minor superficial bleeding or crying, and irritability during acupuncture was experienced by some Wong and Sun 2010 [42 ] 25/25 None. Initial crying in fear and possible minor pain occurred in the first few sessions, but patients adapted easily and tolerated the procedure well Wong et al. 2014 [43 ] 12/9 None. Initial crying in fear and possible minor pain occurred in first few sessions, but patients adapted easily and tolerated the procedure well Zhao et al. 2015 [49 ] 30/30 None
C, control group; E, experimental group.