Scutellaria baicalensis Attenuates Airway Remodeling via PI3K/Akt/NF-κB Pathway in Cigarette Smoke Mediated-COPD Rats Model

Figure 5

The effect of SB on airway remodeling assessment. Rats were exposed to CS for 12, 24, and 36 weeks with SB (1.5, 3, and 6 mg/(kg⋅d)) or BUD (0.2 mg/(kg⋅d)). Lung tissue was stained using HE and Masson before being calculated. The thickness of bronchial smooth muscle and PASM in 200 um was quantitated. Data are mean ± SEM . , , compared with the normal control group. , , compared with the COPD model group. , , compared with BUD group. CS = cigarette smoke; SB = Scutellaria baicalensis; BUD = Budesonide; HE = hematoxylin and eosin staining; PASM = pulmonary arteriolar smooth muscle.

(a)

(b)