Scutellaria baicalensis Attenuates Airway Remodeling via PI3K/Akt/NF-κB Pathway in Cigarette Smoke Mediated-COPD Rats Model

Figure 8

The effect of SB on PI3K/AKT/NF-κB pathway. Rats were exposed to CS for 24 weeks with SB (1.5, 3, and 6 mg/(kg⋅d)) or BUD (0.2 mg/(kg⋅d)). Levels of AKT, p-AKT, NF-κB (p65), and p-NF-κB (p-p65) were determined by western blot (WB). Data are mean ± SEM . , , compared with the normal control group. , , compared with the COPD model group. , , compared with BUD group. CS = cigarette smoke; SB = Scutellaria baicalensis; and BUD = Budesonide.