Research Article

Investigation of the Antidiarrheal and Antimicrobial Activities of 80% Methanolic Leaf Extract of Discopodium Penninervum (Hochst.)

Table 3

Evaluation of antidiarrheal activity of methanolic extracts of leaves of Discopodium Penninervum against castor oil induced diarrhea.

Gp no. Dose Onset of diarrheaTotal number of faecesWeight of fresh fecal output

-23.83±8.5211.67±2.801.38±0.3
100mg/kg52.00±2.837.83±1.470.98±0.06
200mg/kg58.17±2.046.67±1.630.89±0.06
400mg/kg84.67±7.615.17±1.170.65±0.21
3mg/kg138±33.753.00±1.790.46±0.32

Key: data are expressed as means ± SEM for six mice per a group; means p<0.01; means p<0.05.