Research Article

The Effect of a Hydrolyzed Polysaccharide Dietary Supplement on Biomarkers in Adults with Nonalcoholic Fatty Liver Disease

Table 3

White blood cell subsets and platelets at baseline and 45 and 90 days.

MeasureReference rangeTimeRBACPlacebo

White blood cells (103/μL4.3–10.3Baseline6.7 ± 2.7 (3.6, 13.8)5.5 ± 1.1 (2.5, 6.4)
45 days6.5 ± 2.5 (3.8, 12)5.8 ± 1.5 (4.2, 9)
90 days6.7 ± 2.8 (3.4, 13.4)6 ± 1.6 (2.8, 8.4)

Neutrophils (%)41–73Baseline53.1 ± 9.2 (37.7, 65.7)56.7 ± 6.1 (45, 67.6)
45 days50.8 ± 10.2 (25.8, 64.5)56.4 ± 5.9 (45.8, 65.3)
90 days48.5 ± 10.6 (25.5, 66.9)56.6 ± 6.1 (47.6, 64.8)

Lymphocytes (%)19.4–44.9Baseline36.8 ± 7.5 (26, 51.2)32.7 ± 5.7 (22.9, 42.6)
45 days37.9 ± 9.6 (23.6, 61.8)32.8 ± 6.5 (20.2, 42)
90 days38.6 ± 9.6 (22.2, 60.1)32.4 ± 4.9 (29.4, 39)

Neutrophil/lymphocyte ratioNoneBaseline1.5 ± 0.6 (0.7, 2.5)1.8 ± 0.5 (1.1, 2.5)
45 days1.5 ± 0.6 (0.4, 2.7)1.8 ± 0.6 (1.1, 3.0)
90 days1.4 ± 0.7 (0.4, 3.0)1.8 ± 0.4 (1.2, 2.3)

Monocytes (%)+5.1–10.9Baseline7.3 ± 2.1 (3.5, 11.8)7.3 ± 4 (3.6, 18.5)
45 days7.8 ± 1.2 (5.9, 10.1)8.1 ± 3.3 (5.5, 16.5)
90 days9.1 ± 1.3 (6.9, 11.3)8.1 ± 4.4 (4.5, 19.4)

Eosinophils (%0.9–6.0Baseline2.5 ± 1.3 (1.2, 4.9)2.9 ± 1.4 (1.1, 5.5)
45 days3 ± 1.2 (2.1, 5.5)2.2 ± 1.1 (0.5, 4.1)
90 days3.3 ± 1.5 (1.6, 6)2.2 ± 1.2 (0.8, 4.4)

Platelets (103/μL156–373Baseline254.8 ± 90.5 (180, 511)196.9 ± 61.9 (81, 292)
45 days225.6 ± 46.7 (170, 311)194.3 ± 65.3 (55, 267)
90 days229.5 ± 51.8 (176, 351)210.4 ± 91.6 (65, 398)

Note. Values are mean ± standard deviation (minimum, maximum). Percent change difference from baseline to 90 days; +percent change difference from 45 days to 90 days; percent change difference from baseline to 45 days.