Research Article

Evaluation of the Wound Healing Activity of the Crude Extract of Leaves of Acanthus polystachyus Delile (Acanthaceae)

Table 4

Effect of topical application of the 80% methanolic extract ointment of A. polystachyus on the period of epithelialization of infected wound model in mice.

Treatment groups Period of epithelialization (days)

Simple ointment baseFR
Nitrofurazone (0.2 % w/w)16.17 ± 1.83
5% crude extract ointment (w/w)17.00 ± 0.86
10% crude extract ointment (w/w)14.17 ± 1.17

Note: FR: failed to reepithelize. Values are expressed as mean ± SEM (n = 6), one-way ANOVA. Compared to negative control (simple ointment); compared to 5% ointment; P < 0.05 and P < 0.001.