Metabolic Profiling Analysis of the Alleviation Effect of the Fractions of Niuhuang Jiedu Tablet on Realgar Induced Toxicity in Rats

Figure 5

PCA scores plot (a) derived from ¹H NMR spectra of urine from the eight groups (, ). PLS-DA scores plot and corresponding loadings plot based on ¹H NMR spectra of urine from control group, Realgar group, NJT-PET group, NJT-25 group, NJT-50 group, and NJT-95 group ((b) and (c) -intercept of 0.375, -intercept of −0.213) and from control group, Realgar group, NJT group, and NJT-75 group. ((d) and (e) -intercept of 0.334, -intercept of −0.191). Control group (black square), Realgar group (red triangle), NJT group (blue square), NJT-PET group (green triangle), NJT-25 group (yellow triangle), NJT-50 group (blue triangle), NJT-75 group (red square), and NJT-95 group (black triangle).

(a)

(b)

(c)

(d)

(e)