Review Article
Antitumor Research of the Active Ingredients from Traditional Chinese Medical Plant Polygonum Cuspidatum
Figure 6
Resveratrol and cancer pain. Resveratrol can mitigate morphine tolerance through restraining neuroinflammation and downregulating NMDAR NR1 and NR2B subunit expression. The suppression of spinal glial activation and CX3CR1 upregulation is another mechanism of the analgesic effects of resveratrol.