Review Article
Antitumor Research of the Active Ingredients from Traditional Chinese Medical Plant Polygonum Cuspidatum
Figure 8
Antitumor effects of emodin and chrysophanic acid. Emodin can inhibit the growth of oral cancer cells by reducing Sp1 and inducing caspase-dependent apoptosis. Chrysophanic acid has anticancer activity through its effect on EGFR/mTOR mediated signaling transduction pathway.