Review Article

Antitumor Research of the Active Ingredients from Traditional Chinese Medical Plant Polygonum Cuspidatum

Figure 8

Antitumor effects of emodin and chrysophanic acid. Emodin can inhibit the growth of oral cancer cells by reducing Sp1 and inducing caspase-dependent apoptosis. Chrysophanic acid has anticancer activity through its effect on EGFR/mTOR mediated signaling transduction pathway.