Table 4: Summary of GO terms for differentially expressed genes between drug and model groups.

Ontology sourceGO IDGO termTerm value

Biological processGO: 1902600Hydrogen ion transmembrane transport
GO: 0070646Protein modification by small protein removal

Cellular componentGO: 0005732Small nucleolar ribonucleoprotein complex
GO: 0005685U1 snRNP
GO: 0044391Ribosomal subunit
GO: 0005753Mitochondrial proton-transporting ATP synthase complex
GO: 0045259Proton-transporting ATP synthase complex
GO: 0016469Proton-transporting two-sector ATPase complex
GO: 0044455Mitochondrial membrane part

Molecular functionGO: 0015078Hydrogen ion transmembrane transporter activity
GO: 0004129Cytochrome-c oxidase activity
GO: 0015002Heme-copper terminal oxidase activity
GO: 0016676Oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GO: 0008553Hydrogen-exporting ATPase activity, phosphorylative mechanism
GO: 0016675Oxidoreductase activity, acting on a heme group of donors
GO: 0030515snoRNA binding
GO: 0036442Hydrogen-exporting ATPase activity
GO: 0016830Carbon-carbon lyase activity
GO: 0016814Hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
GO: 0000062Fatty-acyl-CoA binding
GO: 0019783Ubiquitin-like protein-specific protease activity
GO: 0019843rRNA binding

22 GO terms are significantly enriched by the 289 changed genes after model group treated with ZGW rat serum.