Electroacupuncture Ameliorates Cognitive Deficit and Improves Hippocampal Synaptic Plasticity in Adult Rat with Neonatal Maternal Separation

Figure 3

Effect of EA on performance in the fear conditioning task. (a) EA ameliorated impairment in contextual fear memory in rats with neonatal MS, /group; ; , , and versus control group; versus MS group; one-way ANOVA. (b) There was no impairment in fear conditioning to tone in rats suffered maternal separation. CS represents condition stimulus, such as sound combined with an aversive unconditioned stimulus (foot shock); pre-CS represents a 120 sec pause without stimulation. /group; ; ; two-way ANOVA.

(a)

(b)