QiDiTangShen Granules Reduced Diabetic Kidney Injury by Regulating the Phosphorylation Balance of the Tyrosine and Serine Residues of Insulin Receptor Substrate 1

Figure 3

Morphological changes of the kidney of mice in different groups. (a) HE and Masson’s trichrome staining of renal sections. (b) Percentage of areas showing fibrosis. Sections stained with Masson’s trichrome staining were used to calculate the percentage of areas showing renal fibrosis. At 200x magnification, 10 nonoverlapping fields showing the renal interstitium were selected in each section, the ratio of the blue areas indicating the collagen fibers to the total area was calculated, and the mean value of each treatment group was compared. C57BL/6, the normal control group; db/db, the diabetic nephropathy (DN) model group; db/db + v and db/db + valsartan, the valsartan intervention group; db/db + Q and db/db + QDTS, the QDTS granules intervention group. n = 3 for each group. P < 0.01 compared with the normal control, P < 0.01 compared with the DN model group.

(a)

(b)