The Effect of Berberine on Polycystic Ovary Syndrome Patients with Insulin Resistance (PCOS-IR): A Meta-Analysis and Systematic Review

Table 3

The result of meta-analysis regarding the effect of BBR versus MET.

Indices	SMD	95CI	P	Trials involved
BMI^◆1♣1◆2♣2◆3♣3	-0.158^◤☆	-0.446~1.130	0.281^◎	No. 1, No. 2, No. 3
FSH	0.184^◥	-0.305~0.673	0.461^◎	No. 1, No. 2, No. 3
LH^◆1◆3	-0.130^◥☆	-0.688~0.429	0.649^◎	No. 1, No. 2, No. 3
T^◆1◆2♣2◆3	-0.516^◥☆	-1.088~0.055	0.077^◎	No. 1, No. 2, No. 3
HOMA-IR^◆1♣1◆2♣2◆3	-0.188^◤☆	-0.476~0.100	0.201^◎	No. 1, No. 2, No. 3
TC^◆1♣1◆2♣2◆3♣3	-1.233^◥☆	-2.912~0.446	0.150^◎	No. 1, No. 2, No. 3
TG^◆1♣1◆3♣3	0.045^◤	-0.243~0.332	0.761^◎	No. 1, No. 2, No. 3
LDL-C^◆1♣1◆2♣2◆3♣3	-0.701^◥☆	-1.630~0.229	0.140^◎	No. 1, No. 2, No. 3
HDL-C	0.148^◥	-0.984~1.280	0.798^◎	No. 1, No. 2, No. 3

Notes:
significant statistical difference (P<0.05) between final value and baseline in BBR group was reported by trial No. x.
significant statistical difference (P<0.05) between final value and baseline in MET group was reported by trial No. x.
^◤:fixed effect model;^◥:random effect model.
^◎: P>0.05.
^☆: BBR group showed a greater change than MET before and after treatment.