Classification of Gan Dan Shi Re Pattern and Gan Shen Yin Xu Pattern in Patients with Hepatitis B Cirrhosis Using Metabonomics
Table 3
Different metabolites between LP and HG.
No.
Differential metabolites
VIP
P
FC
Tendency
Class
1
Beta-alanine
2.6
≤0.001
0.32
↓
Amino acid
2
Creatinine
1.8
≤0.001
0.68
↓
Amino acid
3
L-Asparagine
1.6
≤0.001
1.33
↑
Amino acid
4
L-Tyrosine
1.7
0.001
1.44
↑
Amino acid
5
D-Threitol
1.8
≤0.001
1.70
↑
Carbohydrate
6
Rhamnose
2.0
≤0.001
1.72
↑
Carbohydrate
7
L-Sorbose
1.7
≤0.001
0.53
↓
Carbohydrate
8
D-Fructose
1.7
≤0.001
0.53
↓
Carbohydrate
9
Gluconolactone
1.8
≤0.001
1.86
↑
Carbohydrate
10
Sucrose
1.6
≤0.001
2.01
↑
Carbohydrate
11
D-Maltose
1.7
≤0.001
79.59
↑
Carbohydrate
12
Pelargonic acid
2.0
≤0.001
1.90
↑
Fatty acid
13
Tetracosanoic acid
1.8
≤0.001
1.32
↑
Fatty acid
14
Normetanephrine
1.7
≤0.001
0.72
↓
Hormone
15
Tryptamine
1.6
≤0.001
0.62
↓
Indoles
16
Uracil
1.6
0.001
1.97
↑
Nucleotide
17
Inosine
2.0
≤0.001
5.15
↑
Nucleotide
18
Malic acid
1.6
0.002
1.78
↑
Organic acids
19
Oxoglutaric acid
1.8
≤0.001
3.22
↑
Organic acids
20
Taurine
1.8
≤0.001
0.45
↓
Organic acids
21
Citric acid
1.8
≤0.001
2.51
↑
Organic acids
22
Isocitric acid
2.1
≤0.001
2.76
↑
Organic acids
FC, fold change; VIP, variable importance in projection. ↑, the content of this metabolite was higher in the group of latent pattern (LP) than in the healthy group; ↓, the content of this metabolite was lower.