Tanshinone IIA Attenuates Diabetic Peripheral Neuropathic Pain in Experimental Rats via Inhibiting Inflammation

<div><i>The effect of Tanshinone IIA on the protein expression of IL-1<i>β</i>, IL-6, TNF-<i>α</i>, and IL-10 in the DRG from experiment rats</i>. The protein levels of IL-1<i>β</i>, IL-6, TNF-<i>α</i>, and IL-10 were determined by Western blot. (a) Western blot results of the IL-1<i>β</i>, IL-6, TNF-<i>α</i>, and IL-10. (b) The target protein bands were densitometrically analyzed after normalization to <i>β</i>-actin. Each experiment was repeated three times and similar results were obtained. CTL, normal rats; DM + Veh, DM rats treated with vehicle; DM + TIIA, DM rats treated with Tanshinone IIA. 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Evidence-Based Complementary and Alternative Medicine

fig4

Figure 4

Figure 4: Tanshinone IIA Attenuates Diabetic Peripheral Neuropathic Pain in Experimental Rats via Inhibiting Inflammation 