Antimycobacterial Activity and Safety Profile Assessment of Alpinia galanga and Tinospora cordifolia
Table 3
Effect of the extracts on the relative organ weight of mice after 12 weeks treatment.
Parameters
Extracts
Control
AGDC
%
AGET
%
TCDC
%
TCET
%
166 mg/kg
change
193 mg/kg
change
189 mg/kg
change
170 mg/kg
change
Heart
0.11 ± 0.006
0.15 ± 0.004
36↑
0.15 ± 0.01
36↑
0.13 ± 0.006
18↑
0.12 ± 0.008
9↑
Liver
1.29 ± 0.07
1.47 ± 0.02
14↑
1.48 ± 0.01
15↑
1.14 ± 0.32
11↓
1.46 ± 0.02
13↑
Lungs
0.39 ± 0.01
0.45 ± 0.001
15↑
0.44 ± 0.02
12↑
0.36 ± 0.006
8↓
0.40 ± 0.01
2↑
Spleen
0.11 ± 0.007
0.15 ± 0.01
36↑
0.12 ± 0.01
9↑
0.13 ± 0.006
18↑
0.13 ± 0.007
18↑
Kidney
0.32 ± 0.01
0.38 ± 0.01
18↑
0.44 ± 0.01
37↑
0.33 ± 0.003
3↑
0.44 ± 0.008
37↑
Testis
0.23 ± 0.007
0.26 ± 0.01
13↑
0.28 ± 0.01
21↑
0.23 ± 0.02
0.27 ± 0.02
17↑
All values represent mean ± SEM. p < 0.05; p < 0.01; p < 0.001; ANOVA, followed by Dunnett’s multiple comparison test. Test value compared with control group
