Antimycobacterial Activity and Safety Profile Assessment of Alpinia galanga and Tinospora cordifolia
Table 6
Effect of the extracts on lipid profile and total protein of male and female mice in chronic toxicity test.
Parameters
Extracts
Control
AGDC
%
AGET
%
TCDC
%
TCET
%
166 mg/kg
change
193 mg/kg
change
189 mg/kg
change
170 mg/kg
change
Cholesterol
108.0 ± 3.43
170.75 ± 4.4
58↑
85.7 ± 4.37
21↓
77.9 ± 4.95
28↓
133.75 ± 3.42
24↑
Triglycerides(mg/dl)
60.6 ± 2.29
147.0 ± 5.36
143↑
39.92 ± 1.38
34↓
43.71 ± 2.24
28↓
119.25 ± 6.1
97↑
HDL(mg/dl)
51.0 ± 0.87
87.55 ± 5.4
72↑
37.82 ± 2.21
26↓
39.25 ± 1.2
23↓
82.1 ± 3.3
61↑
VLDL(mg/dl)
12.12 ± 0.45
29.4 ± 107
143↑
7.98 ± 0.27
34↓
8.75 ± 0.44
28↓
23.85 ± 1.23
97↑
LDL(mg/dl)
44.64 ± 4.35
60.3 ± 6.66
35↑
35.34 ± 1.53
20↓
26.47 ± 1.33
41↓
28.67 ± 4.98
36↓
Total Protein (g/dl)
5.3 ± 0.14
3.05 ± 0.11
42↓
3.7 ± 0.18
30↓
6.25 ± 0.40
18↑
3.67 ± 0.320
31↓
All values represent mean ± SEM. p < 0.05; p < 0.01; p < 0.001; ANOVA, followed by Dunnett’s multiple comparison test. Test value compared with control group
