Table of Contents Author Guidelines Submit a Manuscript
Corrigendum

A corrigendum for this article has been published. To view the corrigendum, please click here.

Evidence-Based Complementary and Alternative Medicine
Volume 2018, Article ID 2968025, 10 pages
https://doi.org/10.1155/2018/2968025
Review Article

The Therapeutic Effects of a Traditional Chinese Medicine Formula Wuzi Yanzong Pill for the Treatment of Oligoasthenozoospermia: A Meta-Analysis of Randomized Controlled Trials

1Department of Obstetrics and Gynecology, Prince of Wales Hospital, The Chinese University of Hong Kong, Sha Tin, Hong Kong
2Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Sha Tin, Hong Kong
3School of Chinese Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong
4Hong Kong Institute of Integrative Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Sha Tin, Hong Kong

Correspondence should be addressed to David Yiu Leung Chan; kh.ude.khuc@61lycdrd

Received 9 August 2017; Accepted 18 December 2017; Published 17 January 2018

Academic Editor: Kazim Sahin

Copyright © 2018 Ming Peng Zhao et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. M. De Kretser and H. W. G. Baker, “Infertility in men: recent advances and continuing controversies,” The Journal of Clinical Endocrinology & Metabolism, vol. 84, no. 10, pp. 3443–3450, 1999. View at Google Scholar · View at Scopus
  2. N. Alam, “Male factor infertility—basics revisited,” Journal of the College of Physicians and Surgeons Pakistan, vol. 19, no. 4, pp. 205-206, 2009. View at Google Scholar · View at Scopus
  3. WHO, WHO Laboratory Manual for The Examination and Processing of Human Semen, World Health Organization, Geneva, Switzerland, 5th edition, 2010.
  4. A. Jungwirth, A. Giwercman, H. Tournaye et al., “European association of urology guidelines on male infertility: the 2012 update,” European Urology, vol. 62, no. 2, pp. 324–332, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. D. A. Adamopoulos, “Medical treatment of idiopathic oligozoospermia and male factor subfertility,” Asian Journal of Andrology, vol. 2, no. 1, pp. 25–32, 2000. View at Google Scholar · View at Scopus
  6. Y. Chang, K.-C. Jeng, K.-F. Huang et al., “Effect of cordyceps militaris supplementation on sperm production, sperm motility and hormones in Sprague-Dawley rats,” American Journal of Chinese Medicine, vol. 36, no. 5, pp. 849–859, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. C.-C. Yang, J.-C. Chen, G.-W. Chen, Y.-S. Chen, and J. G. Chung, “Effects of Shao-Fu-Zhu-Yu-Tang on motility of human sperm,” American Journal of Chinese Medicine, vol. 31, no. 4, pp. 573–579, 2003. View at Publisher · View at Google Scholar · View at Scopus
  8. J.-C. Chen, L.-D. Chen, W. Tsauer, C. C. Tsai, B.-C. Chen, and Y.-J. Chen, “Effects of Ginsenoside Rb2 and Rc on inferior human sperm motility in vitro,” American Journal of Chinese Medicine, vol. 29, no. 1, pp. 155–160, 2001. View at Publisher · View at Google Scholar · View at Scopus
  9. L. Kong and M. Li, “The origin of the traditional Chinese medicine ‘Wuzi Yanzong pill’ formula,” Chinese Journal of Basic Medicine in Traditional Chinese Medicine, vol. 15, no. 01, pp. 67-68, 2009. View at Google Scholar
  10. A. Liberati, D. G. Altman, J. Tetzlaff et al., “The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration,” Journal of Clinical Epidemiology, vol. 62, no. 10, pp. e1–e34, 2009. View at Publisher · View at Google Scholar
  11. D. F. Stroup, J. A. Berlin, S. C. Morton et al., “Meta-analysis of observational studies in epidemiology: a proposal for reporting,” Journal of the American Medical Association, vol. 283, no. 15, pp. 2008–2012, 2000. View at Publisher · View at Google Scholar · View at Scopus
  12. X. J. Chen, “Clinical observation of treatment in men with oligoasthenospermia with Wuzi Yanzong Bolu,” Journal of Clinical Medicine in Practice, vol. 15, no. 11, pp. 116–120, 2011. View at Google Scholar
  13. H. L. Yu, M. X. Chang, S. Y. Zhou, H. H. Cao, Y. J. Yang, and M. Li, “The effect of Wuzi Yanzong formula on sperm quality and mortality,” Chinese Journal of Andrology, vol. 29, no. 10, pp. 61-62, 2015. View at Google Scholar
  14. E. Kessopoulou, H. J. Powers, K. K. Sharma et al., “A double-blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated male infertility,” Fertility and Sterility, vol. 64, no. 4, pp. 825–831, 1995. View at Publisher · View at Google Scholar · View at Scopus
  15. C. Rolf, T. G. Cooper, C. Yeung, and E. Nieschlag, “Antioxidant treatment of patients with asthenozoospermia or moderate oligoasthenozoospermia with high-dose vitamin C and vitamin E: a randomized, placebo-controlled, double-blind study,” Human Reproduction, vol. 14, no. 4, pp. 1028–1033, 1999. View at Publisher · View at Google Scholar · View at Scopus
  16. E. Greco, M. Iacobelli, L. Rienzi, F. Ubaldi, S. Ferrero, and J. Tesarik, “Reduction of the incidence of sperm DNA fragmentation by oral antioxidant treatment,” Journal of Andrology, vol. 26, no. 3, pp. 349–353, 2005. View at Publisher · View at Google Scholar · View at Scopus
  17. J. P. T. Higgins, S. Green, and Cochrane Collaboration, Cochrane Handbook for Systematic Reviews of Interventions, Wiley-Blackwell, Hoboken, NJ, USA, 2008.
  18. S. P. Hozo, B. Djulbegovic, and I. Hozo, “Estimating the mean and variance from the median, range, and the size of a sample,” BMC Medical Research Methodology, vol. 5, article 13, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. J. P. T. Higgins, S. G. Thompson, J. J. Deeks, and D. G. Altman, “Measuring inconsistency in meta-analyses,” British Medical Journal, vol. 327, no. 7414, pp. 557–560, 2003. View at Publisher · View at Google Scholar · View at Scopus
  20. J. P. T. Higgins and S. G. Thompson, “Quantifying heterogeneity in a meta-analysis,” Statistics in Medicine, vol. 21, no. 11, pp. 1539–1558, 2002. View at Publisher · View at Google Scholar · View at Scopus
  21. Z. Q. Wang, B. Liang, and Y. Q. Huang, “The effect of Wuzi Yanzong Pill on male infertility,” Journal of Guangxi Medical University, vol. 27, no. 02, pp. 291-292, 2010. View at Google Scholar
  22. N. H. Li, “The treatment effect of Wuzi Yanzong pill on 60 infertility males,” China Pharmaceuticals, vol. 22, no. 04, pp. 84-85, 2013. View at Google Scholar
  23. W. L. Yao and S. H. Chen, “Clinical study on effect of kidney essence granule on improvement of DNA integrity in patients with idiopathic weak sperm,” Chinese Journal of Biochemistry and Molecular Biology, vol. 35, no. 10, pp. 25–28, 2015. View at Google Scholar
  24. C. L. Zhang, W. Y. Qu, L. Y. Liu, and M. Wang, “Effect and mechanism of Wuzi Yanzong Wan on sperm DNA damage and sperm vitality,” Liaoning University of Traditional Chinese Medicine, vol. 19, no. 01, pp. 206–208, 2017. View at Google Scholar
  25. J. Zhang, “Wuzi Yanzong Pills in the treatment of abnormal sperm male infertility for 300 cases,” Chinese Medicine Modern Distance Education of China, vol. 15, no. 02, pp. 47-48, 2017. View at Google Scholar
  26. Y.-P. Xu, B.-X. Liu, X.-P. Zhang, C.-W. Yang, and C.-H. Wang, “A Chinese herbal formula, Wuzi Yanzong Pill, improves spermatogenesis by modulating the secretory function of Sertoli cells,” Chinese Journal of Integrative Medicine, vol. 20, no. 3, pp. 194–199, 2014. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Lammers, C. Splingart, P. Barrière, M. Jean, and T. Fréour, “Double-blind prospective study comparing two automated sperm analyzers versus manual semen assessment,” Journal of Assisted Reproduction and Genetics, vol. 31, no. 1, pp. 35–43, 2014. View at Publisher · View at Google Scholar · View at Scopus
  28. WHO, WHO Laboratory Manual for The Examination of Human Semen And Sperm-Cervical Mucus Interaction, Cambridge University Press, Cambridge, UK, 4 edition, 1999, Published on behalf of the World Health Organization by Cambridge University Press, Cambridge, UK.
  29. H.-J. Ji, D.-M. Wang, Y.-P. Wu et al., “Wuzi Yanzong pill, a Chinese polyherbal formula, alleviates testicular damage in mice induced by ionizing radiation,” BMC Complementary and Alternative Medicine, vol. 16, no. 1, article no. 509, 2016. View at Publisher · View at Google Scholar · View at Scopus
  30. Q. An and L. Zou, “A meta-analysis of the Chinese medicine Wuziyanwan for treatment of oligospermia and asthenospermia,” The Chinese Journal of Human Sexuality, vol. 24, no. 1, pp. 84–89, 2015. View at Google Scholar