The Therapeutic Effects of a Traditional Chinese Medicine Formula Wuzi Yanzong Pill for the Treatment of Oligoasthenozoospermia: A Meta-Analysis of Randomized Controlled Trials
Table 2
Results of meta-analysis comparison of WZYZ pill and placebo or vitamin control.
Outcome measures
Studies numbers
WZYZ pill participant numbers
Control participants numbers
MD (95% CI)
value
Study heterogeneity
df
, %
value
Sperm concentration
5
509
451
5.99 [2.12, 9,85]
0.002
79.74
4
95
<0.00001
Sperm mobility
5
509
451
4.57 [0.47, 8.68]
0.03
152.97
4
97
<0.00001
Sperm morphology
2
66
56
−1.93 [−4.87, 1.01]
0.20
0.79
1
0
0.38
Sperm DFI
2
66
56
−3.82 [−6.45, −1.19]
0.004
0.18
1
0
0.67
Activity of acrosomal enzyme
2
109
81
28.27 [12.41, 44.14]
0.0005
32.74
1
97
<0.00001
Sperm volume
2
340
310
0.68 [0.64, 0.72]
<0.00001
2.69
1
63
<0.1
WZYZ = Wuzi Yanzong; MD = mean difference; df = degree of freedom; CI = confidence interval; DFI = DNA fragmentation index.
