Astragalus membranaceus and Salvia miltiorrhiza Ameliorate Lipopolysaccharide-Induced Acute Lung Injury in Rats by Regulating the Toll-Like Receptor 4/Nuclear Factor-Kappa B Signaling Pathway

Figure 5

Effects of AM/SM on the TLR-4, IRAK-1 and NF-κB protein expression of lung tissues. (Immunohistochemistry-stain, magnification ×400). (a) Lung sections from sham group, LPS group, Dex group, herb I group, and herb II group were stained with TLR-4, IRAK-1, and NF-κB antibody and hematoxylin. Positive products were represented by a brown-yellow color (black Arrow). (b) IOD value of TLR-4 protein expression; (c) IOD value of IRAK-1 protein expression; (d) IOD value of NF-κB protein expression. Values were expressed as mean ± SD (). versus sham group. versus LPS group. and versus Dex group. ^▽ and ^▽▽ versus group I.

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