Research Article

Astragalus membranaceus and Salvia miltiorrhiza Ameliorate Lipopolysaccharide-Induced Acute Lung Injury in Rats by Regulating the Toll-Like Receptor 4/Nuclear Factor-Kappa B Signaling Pathway

Figure 7

Schematic plot of the possible mechanisms behind the protective and therapeutic effects of AM/SM on LPS-induced ALI. AM/SM downregulated the TLR-4/IRAK-1/NF-κB signaling pathway; then inflammatory cytokines were decreased. Pulmonary edema and lung tissue damage were alleviated at last.