Paeonol Ameliorates Ovalbumin-Induced Asthma through the Inhibition of TLR4/NF-κB and MAPK Signaling

Figure 5

Changed expression of p-P38 and p-ERK in asthma and paeonol treatment. (a) The expression of p-ERK, ERK, p-P38, and P38 was analysed by immune blot. GAPDH was utilized as the standard control. (b) The band signal strengths of p-ERK and ERK were expressed as a ratio to ERK and GAPDH, respectively (n= 4 per group). (c) The band signal strengths of p-P38 and P38 were expressed as a ratio to P38 and GAPDH, respectively. The data were expressed as the means ± SEM (n = 4 per group). Extracellular signal-regulated kinase, ERK; glyceraldehyde-3-phosphate dehydrogenase, GAPDH; ovalbumin, OVA; control, Con; montelukast sodium, Mon. P < 0.01 compared with Con, #P < 0.05 compared with OVA, and †P < 0.01 compared with OVA.

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