Evidence-Based Complementary and Alternative Medicine

Research Article

In Vitro Wound Healing Potential of Stem Extract of Alternanthera sessilis

Table 1

Total compounds identified in the crude extract of stem part of A. sessilis using GC-MS analysis with its retention time, peak area, and reported biological activities.


Peak number	Compounds		(%)	Reported biological activities	Citations

1.	Pentanal <n->	2.612	1.95	Antimicrobial	[10].

2.	Formic acid, 2-propenyl ester	2.660	1.71	No reported activity

4.	Butyrolactone	7.868	0.69	Anti-inflammatory	[11].

6.	Furfural <5-methyl->	9.532	1.3	Antibacterial Antifungal	[12, 13].

7.	Phenylacetaldehyde	13.139	1.09	Antimicrobial Anti-inflammatory Antineoplastic	[14, 15].

8.	2,4-Dihydroxy-2,5-dimethyl-3(2H)-furan-3-one	17.793	8.92	Antioxidant	[16].

9.	1,2,4-Trioxolane,3-phenyl-	19.295	5.99	Antibacteria Antifungal Antiprotozoal Antitumor Immunomodulator	[17].

19.	Phenol, 2-ethyl-4,5-dimethyl-	25.763	5.00	Antibacterial Anti-inflammatory	[18].

21.	L-glutamic acid	29.262	5.04	Acts as amino acid Fuel for metabolism Anticancer Anti-inflammation Immunomodulator Neurotransmitter	[19].

22	Glutamine, L-	32.014	0.55	Anti-inflammation	[20].

27.	Neophytadiene	46.544	1.08	Antipyretic Antianalgesic Anti-inflammatory Antimicrobial Antioxidant	[21].

29.	Phytone	46.930	1.29	Antioxidant Anti-inflammatory	[22, 23].

30.	Hexadecanoate <methyl->	49.924	0.92	Antifungal Anti-inflammatory	[24, 25].

31.	Hexadecanoic acid <n->	51.394	7.21	Antibacterial Antifungal Anti-inflammatory Antioxidant Hypocholesterolemic Nematicide Pesticide Antiandrogenic Hemolytic, 5-Alpha reductase inhibitor Mosquito larvicide	[26].

33.	Palmitate <ethyl->	52.193	5.65	Antioxidant Anticancer	[27, 28].

35.	9,12-Octadecadienoic acid (Z,Z)-, methyl ester	55.519	0.76	Anticancer Hypocholesterolemic Nematicide Antiarthritic Hepatoprotective Antiandrogenic Hypocholesterolemic Nematicide 5-Alpha reductase inhibitor Antihistaminic Anticoronary Insectifuge Antieczemic Antiacne	[29, 30].

36.	Phytol	55.977	4.33	Antimicrobial, Anticancer Anti-inflammatory Antidiuretic, Antidiabetic Immunostimulatory	[21].

37.	Z-3,17-Octadecadien-1-ol acetate	57.593	4.32	Antioxidant Hepatoprotective	[31].

38.	11-(3-Ethenylcyclopentyl) undec-10-enoic acid, ethyl ester	57.814	2.22	No reported activity

47.	Sebacic acid, bis(2-ethylhexyl) ester	74.948	0.77	Anti-inflammatory Antimicrobial Protects skin from rash and irritation Restores natural skin humidity level Decreases hyperglycaemia	[32–35].

: retention time; (%): peak area concentration.