Antileishmanial and Immunomodulatory Effect of Babassu-Loaded PLGA Microparticles: A Useful Drug Target to Leishmania amazonensis Infection

Table 2

Minimum inhibitory concentration of babassu-loaded microparticles against promastigote forms of Leishmania amazonensis compared to unloaded microparticles and extract in solution.

Treatment	IC50 (pg/mL)
MMP
Meso	111.4
CMP	71.8
Pentamidine	0.8

(a) MMP: microparticles loaded with babassu mesocarp extract. CMP: unloaded microparticles; Meso: aqueous extract of babassu mesocarp in solution.
(b) IC₅₀: 50% inhibitory concentration of individual samples tested in triplicate. () p<0.05 compared to the other groups.