Evidence-Based Complementary and Alternative Medicine

Research Article

The Clinical Efficacy and Safety of Gumiganghwal-Tang in Knee Osteoarthritis: A Phase II Randomized Double Blind Placebo Controlled Study

Table 3

Comparisons of total WOMAC score (primary end point).
 GMGHT group (n= 61)Placebo group (n= 66)p value
Total WOMAC score   
 Baseline (day =0)55.8 (13.0)54.1 (13.9)0.48
   week45.5 (14.9)51.6 (14.0)0.20
   week37.5(18.2)50.0 (13.7)3.07 x 10−5
   week34.7 (18.1)46.9 (14.5)5.53 x 10−5
Change in total WOMAC score from baseline  
   week-10.3 (11.2)-2.5 (4.6)2.93 x 10−6
   week-18.3 (16.9)-4.1 (5.2)2.38 x 10−8
   week-21.1 (17.5)-7.1 (8.1)1.85 x 10−7
Values are presented as mean (SD) unless otherwise stated.
GMGHT: Gumiganghwal-tang, SD: standard deviation, WOMAC: the Western Ontario and McMaster Universities Arthritis Index.