Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-<i>β</i>1/Smad Signaling Pathway

<div>Astragalosides decreased the levels of collagen-related indicators and <i>α</i>-SMA in liver tissues. (a) By assay of ELISA and real-time PCR, AST was found to decrease the expression of COL-I induced by CCL4 in rats. (b-c) By assay of ELISA and real-time PCR, AST was also found to decrease the expression of COL-III and <i>α</i>-SMA. AST: astragalosides; LY-364947: TGF-<i>β</i> receptor 1 inhibitor. 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Evidence-Based Complementary and Alternative Medicine

fig5

Figure 5

Figure 5: Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-<i>β</i>1/Smad Signaling Pathway 

Evidence-Based Complementary and Alternative Medicine

Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-β1/Smad Signaling Pathway

Figure 5