Development and Application of an UHPLC-MS/MS Method for Comparative Pharmacokinetic Study of Eight Major Bioactive Components from Yin Chen Hao Tang in Normal and Acute Liver Injured Rats

<div><i>Representative DMRM chromatograms for scoparone, scopoletin, geniposide, aloe-emodin, rhein, emodin, chrysophanol, physcion, and their internal standards glibenclamide and wogonin in rat plasma samples</i>. Panel A: a blank plasma sample; panel B: a blank plasma sample spiked with bioactive compounds and ISs at the LLOQ; panel C: a rat plasma sample collected at 30 min after drug administration.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1: Development and Application of an UHPLC-MS/MS Method for Comparative Pharmacokinetic Study of Eight Major Bioactive Components from Yin Chen Hao Tang in Normal and Acute Liver Injured Rats 

Figure 1 | Development and Application of an UHPLC-MS/MS Method for Comparative Pharmacokinetic Study of Eight Major Bioactive Components from Yin Chen Hao Tang in Normal and Acute Liver Injured Rats 