Bufadienolides from<i> Venenum Bufonis</i> Inhibit mTOR-Mediated Cyclin D1 and Retinoblastoma Protein Leading to Arrest of Cell Cycle in Cancer Cells

<div><b>Bufadienolides arrest cell cycle in G1 phase. </b>MCF-7 cells, grown in 10% FBS-RPMI medium in 6-well plates (1×10<sup>5</sup> cells/well), were treated with bufadienolides (0-10<i>μ</i>g/ml) for 24 h, followed by cell cycle analysis.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 3: Bufadienolides from<i> Venenum Bufonis</i> Inhibit mTOR-Mediated Cyclin D1 and Retinoblastoma Protein Leading to Arrest of Cell Cycle in Cancer Cells 

Figure 3 | Bufadienolides from Venenum Bufonis Inhibit mTOR-Mediated Cyclin D1 and Retinoblastoma Protein Leading to Arrest of Cell Cycle in Cancer Cells 