Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2018, Article ID 3416936, 10 pages
https://doi.org/10.1155/2018/3416936
Research Article

WenTong HuoXue Cream Can Inhibit the Reduction of the Pain-Related Molecule PLC-β3 in the Dorsal Root Ganglion of a Rat Model of Diabetic Peripheral Neuropathy

1Traditional Chinese Medicine Hospital, Xinjiang Medical University, Ürümqi, China
2Xinjiang Medical University, Ürümqi, China

Correspondence should be addressed to Li Ma; moc.361@jxgnagvl

Received 11 September 2017; Revised 4 January 2018; Accepted 16 January 2018; Published 11 February 2018

Academic Editor: I-Min Liu

Copyright © 2018 Chengcheng Feng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. S. Han, “Hot Issues of Neuropathic Pain,” Journal of Medical Research, vol. 40, no. 7, pp. 1-2, 2011. View at Google Scholar
  2. H. L. Zhou and C. Q. Yan, “Research progress of diabetic peripheral neuropathy,” Journal of Military Surgeon in Southwest China, vol. 19, no. 1, pp. 81–83, 2017. View at Google Scholar
  3. J. J. Duby, CamPbell R. K., Setter S. M. et al., “Dibaetic neuropaty: an intensive review,” Am J Health-Syst Pharm, vol. 61, no. 2, pp. 160–173, 2004. View at Google Scholar
  4. Z. Jian-hong, Z. Xin-jun, and L. An-kun, “The clinical research into painful diabetic neuropathy treated with wentong huoxue rugao in combination with pancreatic kininogenase enteric-coated tablets,” Henan Traditional Chinese Medicine, vol. 37, no. 4, pp. 663–665, 2017. View at Google Scholar
  5. S.-K. Han, V. Mancino, and M. I. Simon, “Phospholipase Cβ 3 mediates the scratching response activated by the histamine H1 receptor on C-fiber nociceptive neurons,” Neuron, vol. 52, no. 4, pp. 691–703, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. T.-J. S. Shi, S.-X. L. Liu, H. Hammarberg, M. Watanabe, Z.-Q. D. Xu, and T. Hökfelt, “Phospholipase Cβ3 in mouse and human dorsal root ganglia and spinal cord is a possible target for treatment of neuropathic pain,” Proceedings of the National Acadamy of Sciences of the United States of America, vol. 105, no. 50, pp. 20004–20008, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. F. R. Wang, C. L. Xia, and J. Lu, “Researches about Wen Tong Huoxue cream technology,” Xinjiang Traditional Chinese Med, vol. 26, no. 6, pp. 48–50, 2007. View at Google Scholar
  8. T. Klemm and R. Paschke, “Possible genetic reasons for late complications in diabetes mellitus,” Medizinische Klinik - Intensivmedizin und Notfallmedizin, vol. 95, no. 1, pp. 31–39, 2000. View at Publisher · View at Google Scholar · View at Scopus
  9. G. Conti, E. Scarpini, P. Baron et al., “Macrophage infiltration and death in the nerve during the early phases of experimental diabetic neuropathy: a process concomitant with endoneurial induction of IL-1β and p75NTR,” Journal of the Neurological Sciences, vol. 195, no. 1, pp. 35–40, 2002. View at Publisher · View at Google Scholar
  10. X. Y. Leng, X. K. Wang, and Z. H. Li, “Experimental study on treatment of Dan Gui detumescence cream for acute closed soft tissue injury,” Guide of China Medicine, vol. 9, no. 36, pp. 70-71, 2011. View at Google Scholar
  11. B. X. Zhao, “Treatment of diabetic peripheral neuropathy from the aspect of Qi and blood,” Liaoning Journal of Traditional Chinese Medicine, vol. 31, no. 12, pp. 995-996, 2004. View at Google Scholar
  12. H. u. XL and W. H. Zhang, “Discussion about diabetic peripheral neuropathy from the spleen and stomach and phlegm poisoning,” Xin Jiang Traditional Chinese Med, vol. 24, no. 1, pp. 1-2, 2006. View at Google Scholar
  13. M. A. Li, W. Xianmin, C. Qian et al., “Clinical observation on painful diabetic neuropathy treated by wengtong huoxue cream plus limb air-pressure therapy: a report of 30 cases,” Journal of Traditional Chinese Med, vol. 52, no. 19, pp. 1665–1667, 2011. View at Google Scholar
  14. Z. Hai-Ying and Z. Yong-Bo, “Acute cutaneous toxicity, skin irritation and allergy reaction irritation of wen-tong-huo-xue cream,” in Chinese Journal of Spectroscopy Laboratory, vol. 30, pp. 2354–2356, 5 edition, 2013. View at Google Scholar
  15. T.-J. S. Shi, M.-D. Zhang, H. Zeberg et al., “Coenzyme Q10 prevents peripheral neuropathy and attenuates neuron loss in the db-/db- mouse, a type 2 diabetes model,” Proceedings of the National Acadamy of Sciences of the United States of America, vol. 110, no. 2, pp. 690–695, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. C. Hou, T. Kirchner, M. Singer, M. Matheis, D. Argentieri, and D. Cavender, “In Vivo Activity of a Phospholipase C Inhibitor, 1-(6-((17β -3-Methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione (U73122), in Acute and Chronic Inflammatory Reactions,” The Journal of Pharmacology and Experimental Therapeutics, vol. 309, no. 2, pp. 697–704, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. J. Zhongmei and C. Zhuanxin, “Therapeutic effect of combined treatment of mecobalamin and salvia miltiorrhiza ligustrazine on diabetic peripheral neuropathy,” Chinese Journal of Primary Medicine and Pharmacy, vol. 22, pp. 3467–3469, 2015. View at Google Scholar
  18. L. Zhang, “Effect of safflower, alprostadil and mecobalamin in treating diabetic peripheral neuropathy,” Chinese Journal of Trauma Disability Medicine, vol. 23, pp. 98-99, 2015. View at Google Scholar
  19. X. Q. Liang and D. D. Li, “Progress research on pharmacological activities of asarum,” Journal of Henan University of Science & Technology (Medical Science), vol. 29, no. 4, pp. 318–320, 2011. View at Google Scholar