Antidiabetic Activities of Hydromethanolic Leaf Extract of Calpurnia aurea (Ait.) Benth. Subspecies aurea (Fabaceae) in Mice

Table 3

Antihyperglycemic activity of single dose of Calpurnia aurea leaf extract in STZ-induced diabetic mice.

Group	Blood glucose level (mg/dl)
	0 hr	2 hr	4 hr	6 hr	8 hr
DW 10 ml/kg	394.11 ± 31.03	383.06 ± 27.65	396.39 ± 26.71	397.45 ± 18.52	399.61 ± 22.00
CALE 100 mg/kg	377.72 ± 43.57	364.39 ± 35.29	288.83 ± 51.29	261.33 ± 54.28	254.67 ± 48.16
CALE 200 mg/kg	314.39 ± 31.99	291.11 ± 38.52	254.78 ± 56.26	250.06 ± 51.84	246.50 ± 56.51
CALE 400 mg/kg	342.67 ± 58.07	313.39 ± 73.93	266.39 ± 53.99	290.00 ± 57.78	264.72 ± 56.88
GLC 5 mg/kg	368.50 ± 43.02	283.39 ± 39.09	176.61 ± 14.01	171.72 ± 18.27	155.72 ± 13.59

Each value represents mean ± SEM; n=6 for each treatment. Compared to the negative control and compared to baseline blood glucose level. p < 0.05, p < 0.01, and p < 0.001. CALE = Calpurnia aurea leaf extract, DW = distilled water, and GLC = glibenclamide.