Antidiabetic Activities of Hydromethanolic Leaf Extract of Calpurnia aurea (Ait.) Benth. Subspecies aurea (Fabaceae) in Mice

Table 5

Effect of repeated daily doses of the hydromethanolic leaf extract of Calpurnia aurea on body weight of STZ-induced diabetic mice.

Group	Body weight (g)
	Before induction of Diabetes	Baseline	7th day of treatment	14th day of treatment
Diabetic control	28.67 ± 0.95	26.77 ± 0.89	23.88 ± 1.24	20.88 ± 1.15
CALE 100 mg/kg	28.83 ± 1.09	27.98 ± 0.95	25.07 ± 1.06	23.78 ± 0.86
CALE 200 mg/kg	28.83 ± 0.91	26.82 ± 1.18	24.83 ± 0.98	22.97 ± 0.76
CALE 400 mg/kg	28.75 ± 0.96	27.70 ± 0.99	25.00 ± 1.02	23.25 ± 1.16
GLC 5 mg/kg	28.75 ± 0.48	26.07 ± 0.73	25.95 ± 0.71	26.53 ± 0.72
Normal control	29.00 ± 0.47	29.45 ± 0.36	30.03 ± 0.53	30.70 ± 0.59

Each value represents mean ± SEM; n=6 for each group. Compared to the diabetic control, compared to the normal control, and compared to baseline body weight. p < 0.05, p < 0.01, and p < 0.001. CALE = Calpurnia aurea leaf extract and GLC = glibenclamide.