Bushen-Yizhi Formula Alleviates Neuroinflammation via Inhibiting NLRP3 Inflammasome Activation in a Mouse Model of Parkinson’s Disease

Figure 2

BSYZ protects against tyrosine hydroxylase (TH) depletion and dopaminergic neurons neurodegeneration in MPTP-induced mice. (a) Representative images of TH-positive cell immunoreactivity in substantia nigra pars compacta (SNpc) sections. (b) Statistical results for the number of TH-positive neurons in the SNpc. (c) Nissl⁺ neurons in SNpc area and (d) statistical results were shown by Nissl Staining (n = 4 per group). Scale bar: 100 m. Experimental values were expressed as means ± SEM, ^#P < 0.05 and ^##P < 0.01 versus Control group; P < 0.05 and P < 0.01 versus MPTP-treated group.

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