Bushen-Yizhi Formula Alleviates Neuroinflammation via Inhibiting NLRP3 Inflammasome Activation in a Mouse Model of Parkinson’s Disease

Figure 3

BSYZ attenuates neuroinflammation in the MPTP-induced mice. (a) Representative immunofluorescence images of the SNpc stained with anti-Iba-1 (green) and anti-CD68 antibody (red). (b) Representative immunofluorescence images of the SNpc section stained with anti-GFAP antibody. (c) Statistical results for the relative GFAP-positive cells in the SNpc. (d) Statistical results for the relative number of Iba-1 and CD68 double positive cells in the SNpc. (e) The mRNA levels of proinflammatory factors in midbrain. Experimental values were expressed as means ± SEM, ^#P < 0.05, ^##P < 0.01 versus control group, , versus MPTP group.

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