Bushen-Yizhi Formula Alleviates Neuroinflammation via Inhibiting NLRP3 Inflammasome Activation in a Mouse Model of Parkinson’s Disease

Figure 4

BSYZ suppresses NLRP3 inflammasome signaling in MPTP-induced mice. (a) NLRP3 inflammasomes including NLRP3, ASC, caspase-1, pro-IL-1β, and IL-1β in midbrain were measured by Western blotting and β-actin was detected as an internal control. (b) Quantification data of NLRP3 inflammasome level were detected by Western blot analysis (n = 3 per group). Experimental values were expressed as means ± SEM, ^#P < 0.05, ^##P < 0.01 versus control group. , versus MPTP group.

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