A Literature Review of Women’s Sex Hormone Changes by Acupuncture Treatment: Analysis of Human and Animal Studies

Table 2

Changes in estrogen by acupuncture treatment.

					Changes in hormone level
Author	Year	Subject	Condition	Number	Disease	Acupuncture	Acupuncture method
				of sample (exp/con)		compared to
						disease
Maliqueo et al.	2015	Animal (rat)	PCOS	10/12	▲ E2	▽ E2	EA
Johansson et al.	2013	Human	PCOS	11/14		▽ E1, E1-S, E2	EA+MA
Feng et al.	2012	Animal (rat)	PCOS	40/44		▲ E2	EA+MA
Ma et al.	2017	Animal (rat)	Ovariectomized	8/8	▽ E2	▲ E2	EA
Qin et al.	2013	Animal (rat)	Ovariectomized	8/8		▲ E2	EA
Yao et al.	2007	Animal (rat)	Ovariectomized	8/8		▲ E2	EA
Zhao et al.	2004	Animal (rat)	Ovariectomized	10/12		▲ E2	EA
Zhao et al.	2003	Animal (rat)	Ovariectomized	10/12		▲ E2	EA
Sunay et al.	2011	Human	Menopausal syndrome	27/26	▽ E2	▲ E2	MA
Qu et al.	2007	Human	Menopausal syndrome	36/31		≒ Estrogen	MA
Dong et al.	2001	Human	Menopausal syndrome	11		≒ E2	MA
Wang et al.	2016	Human	Diminished ovarian reserve	21	▽ E2	▲ E2	EA
Zhou et al.	2013	Human	Primary ovarian insufficiency	11	▽ E2	▲ E2	EA
Zhang et al.	2007	Animal (rat)	Pubertal development	5/4	▽ E2	▲E2	EA

▲ Increased, ▽ decreased, and ≒ not significant