Spleen-Kidney Supplementing Formula Alleviates Renal Fibrosis in Diabetic Rats via TGF-β1-miR-21-PTEN Signaling Pathway

Figure 7

Effects of SKSF on the mRNA expression of miR-21. Data are expressed as mean ± SD, n =10 rats per group. (N) Normal group, (M) model group, (Met) metformin group, (SKSFh) Spleen-Kidney Supplementing Formula group at a high dose, (SKSFm) Spleen-Kidney Supplementing Formula group at a medium dose, (SKSFl) Spleen-Kidney Supplementing Formula group at a low dose. ^∗P < 0.05, ^∗∗P <0.01 compared with model group.