Evidence-Based Complementary and Alternative Medicine

Research Article

Hepatoprotective and Anti-Inflammatory Activities of the Cnidoscolus chayamansa (Mc Vaugh) Leaf Extract in Chronic Models

Table 4

Effect of C. chayamansa extract on oxidative stress biomarkers in Balb/C mouse liver tissue with hepatotoxicity induced by antiTB drugs.
Oxidative stress biomarkersAntiTBAntiTB + Silymarin
2.5 mg/kg		 CnCM extract
200 mg/kg400 mg/kg
PCC
(μm carbonyl/g)		403.81±31.28397.46±26.44610.16±14.30517.94±28.87
LPO
(μm MDA/g)		177.82±2.21126.67±5.137.53±6.154.04±3.
Data presented as mean (±) standard error of the mean (SEM). Statistical one-way ANOVA, post hoc Student-Newman-Keuls test (p <0.05); AntiTB; AntiTB + Silymarin 2.5 mg/kg; AntiTB + CnCM 200 mg/kg; AntiTB + CnCM 400 mg/kg; AntiTB: RIF/INH/PZA; PCC: protein carbonyl content; LPO: lipid peroxidation; MDA: malondialdehyde; n = 7.