Hepatoprotective and Anti-Inflammatory Activities of the Cnidoscolus chayamansa (Mc Vaugh) Leaf Extract in Chronic Models

Table 5

Effect of C. chayamansa extract on antioxidant enzymatic activity in Balb/C mouse liver tissue with hepatotoxicity induced by antiTB drugs.

Antioxidant enzymes	AntiTB	AntiTB+ Silymarin; 2.5 mg/kg	CnCM extract
			200 mg/kg	400 mg/kg
SOD; (IU/g)	69.12±12.97	77.43±10.14	59.50±10.20	106.83±
CAT; (IU/g)	8.48±1.65	13.81±6.16	9.47±3.56	16.12±4.

Data presented as mean (±) standard error of the mean (SEM). Statistical analysis, one-way ANOVA, and post hoc Student-Newman-Keuls (SNK) test (p <0.05); AntiTB; AntiTB + Silymarin 2.5 mg/kg; AntiTB + CnCM 200 mg/kg; AntiTB + CnCM 400 mg/kg; AntiTB: antitubercular drugs (RIF, INH, PZA); UI: international units; SOD: superoxide dismutase; CAT: catalase; n = 7.