Induction of Apoptosis and Inhibition of Epithelial Mesenchymal Transition by α-Mangostin in MG-63 Cell Lines

Figure 6

α-Mangostin affected EMT-associated marker. Cells were treated with α-mangostin (0, 10, and 25 μM) for 48 h. (a) Protein expressions of E-cadherin, N-cadherin, slug, and snail were detected by western blot analysis. (b) Relative protein expressions of EMT markers were determined by image J. (c, d) Occludin, fibronectin expressions in the cells treated with α-mangostin (0, 10, and 25 μM) for 48 h were investigated by real-time RT-PCR. versus untreated cells (control).

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