Evidence-Based Complementary and Alternative Medicine

Review Article

Normative Application of Xiyanping Injection: A Systematic Review of Adverse Case Reports

Table 2

Patient details recorded from the included studies.
Case reportDrug batch numberOccurrence time (year/month/ day)Age/Gender (years/female or male)Primary diseaseDosage (mL)Dripping speed (drops per minute)Drug DeliverySolventCombinationMixtureAllergic historyMedication intervalADR type
Danzhu Huang et al. [15]NA2008.6.190.75/MDiarrheaNANAi.v.gtt.NANANoNANAAnaphylactic shock
Wenlan Huang et al. [16]NA2015.2.165/FUpper respiratory tract infections1025i.v.gtt.②NANoNo2minAnaphylactic shock
Bo Chen et al. [17]20070606NA28/FAcute bacillary dysentery12NAi.v.gtt.①NoNoCephalosporin8minAnaphylactic shock
Xiangyu Di et al. [18]NANA7/MMycoplasma pneumonia4NAi.v.gtt.③NANoNANAAnaphylaxis
Hong Lai et al. [19]NA2012.76/MUpper respiratory tract infectionsNANAi.v.gtt.NACeftezoleNoNoNAAnaphylaxis
Zhongying Jian et al. [20]NANA80/MChronic bronchitis850i.v.gtt.②NANoNo2minAnaphylaxis
Zhong Miao et al. [21]2014031103NA1/MBronchitis2NAi.v.gtt.①Mezlocillin sodiumNoNoAfter the infusionAnaphylactic shock
Shujun Hu et al. [22]NANA8/MUpper respiratory tract infections440i.v.gtt.①NANoNA5minAnaphylactic shock
Yingyun Shen et al. [23]20081203NA8/MUpper respiratory tract infections4NAi.v.gtt.①NANoNA50mL remainedAnaphylaxis
Yanli Li et al. [24]201209042012.10.152/MAsthmatic bronchitis3NAi.v.gtt.NANoNoNA20minAnaphylactic shock (vegetative state)
Hongmei Li et al. [25]NA2012.11.239/MUpper respiratory tract infections3NAi.v.gtt.①NANoNA50mL remainedAnaphylactic shock
Xiangping Li et al. [26]200507082005.12.186/MUpper respiratory tract infections2NAi.m.NoNoNoNA5minAnaphylaxis
Wenhua Zhang et al. [27]NANA15/FUpper respiratory tract infections6NAi.v.gtt.①NANoNA1/4 infusedAnaphylaxis
Yuzhi Zuo et al. [28]0511337082007.10.1210/MFever of unknown origin6NAi.v.gtt.①Penicillin, energy mixtureNoNA30minAnaphylaxis
Xinhua An et al. [29]20131223032014.2.73/FAcute bronchitis230i.v.gtt.①Cefuroxime sodium, ribavirin injectionNoNo5minAnaphylactic shock
Jihong Sun et al. [30]NANA11/MAmygdalitis4NAi.v.gtt.NACefotaxime, Xingnaojing injectionNoNoTime of using Xingnaojing injection (after XYP)Anaphylaxis
Yuxin Liu et al. [31]NA2014.3.2053/FAmygdalitis1060i.v.gtt.①AzithromycinNoNoNAConvulsion of unknown origion
Kunna Xiu et al. [32]NANANA/FUpper respiratory tract infections5NAi.v.gtt.①NANoNA2minAnaphylaxis
Hong Yu et al. [33]NA2002.12.3160/MScald with infections12NAi.v.gtt.NANANoSulfonamides3hAnaphylactic shock (death)
Xiaolei Chen et al. [34]200909142010.1.1734/FUpper respiratory tract infections4NAi.v.gtt.①NoNoNo5minAnaphylactic shock
Xiwei Feng et al. [35]NANA2/FBronchopneumonia2NAi.v.gtt.①NANoNA15minAnaphylaxis
Hualing Qiao et al. [36]NANA16/FUpper respiratory tract infections8NAi.v.gtt.①NANoNA10minAnaphylactic shock
Taiyu Wan et al. [37]NA2001.7.330/FUpper respiratory tract infections1040i.v.gtt.④Dexamethasone, VCNoNA2minAnaphylactic shock
Xiaojie Hao et al. [38]NANA5/FUpper respiratory tract infections3NAi.v.gtt.③NANoNo5minAnaphylactic shock
Xiaoru He et al. [39]20100603NA10/FMycoplasma pneumonia6NAi.v.gtt.①Azithromycin, cefoperazoneNoNA20minAnaphylaxis
Cuiling Wang et al. [40]NA2005.6.53.5/MAdenomesenteritis2NAi.v.gtt.NANoNoCephalosporin5minAnaphylaxis
Liqiang Wu et al. [41]20130206022013.9.1939/MUpper respiratory tract infections12NAi.v.gtt.①NANoNo5minAnaphylactic shock
Xiaoqiang Xiong et al. [42]201110242012.2.163/MAmygdalitis2NAi.v.gtt.①NANoNA15minAnaphylactic shock
Fengshu Zhang et al. [43]200909112009.2.61/FUpper respiratory tract infections245i.v.gtt.①NANoNo8minAnaphylactic shock
Guixin Zhang et al. [44]NA2008.2.183.5/FAmygdalitis4NAi.v.gtt.①NANoNo5minAnaphylaxis
Yunying Zhang et al. [45]20090715NA51/FPneumonia8NAi.v.gtt.①NANoNo20minAnaphylactic shock
Fang Dong et al. [46]NANA12/MAmygdalitis8NAi.v.gtt.①NANoNA10minAnaphylactic shock
Fang Dong et al. [47]060417NA0.83/MBronchitis2NAi.v.gtt.①NANoNA5minAnaphylaxis
Xuejin Zhao et al. [48]200409182004.10.1858/FChronic bronchitis850i.v.gtt.②NoNoNo5minAnaphylaxis
Li Zheng et al. [49]20131015NA55/FPneumonia8NAi.v.gtt.①NANoNo20minAnaphylactic shock
Li Zheng et al. [49]20140105NA4/MBronchitis4NAi.v.gtt.①NANoYanhuning injection10minAnaphylactic shock
Liwei Yang et al. [50]NA2012.3.294/FBronchitis2NAi.v.gtt.①NANoNANAAnaphylaxis
Liwei Yang et al. [50]NA2012.8.67/MPneumonia4NAi.v.gtt.①NANoNA20minAnaphylaxis
Xiuju Wang et al. [51]NA2014.6.964/FPneumonia20NAi.v.gtt.①NANoPenicillins15minAnaphylaxis
Xiuju Wang et al. [51]NA2014.6.2335/FBronchiectasia with infections20NAi.v.gtt.①NANoCephalosporin20minAnaphylaxis
Lijuan Wang et al. [52]NA2015.42/FBronchopneumonia2NAi.v.gtt.①NANoNo20minAnaphylaxis
Lijuan Wang et al. [52]NA2015.51.5/MUpper respiratory tract infectionsNANAi.v.gtt.NANANoNo5minAnaphylaxis
Xing Du et al. [53]20050721NA31/FUpper respiratory tract infections4NAi.v.gtt.①AzithromycinNoNA35minAnaphylaxis
Xing Du et al. [53]20050721NA42/MAcute bronchitis4NAi.v.gtt.①PenicillinNoNA3minAnaphylaxis
Xing Du et al. [53]20050721NA4.5/FUpper respiratory tract infections2NAi.v.gtt.①AzithromycinNoNA3minAnaphylaxis
Tian Gao et al. [54]NANA55/FSevere pneumonia1030i.v.gtt.④CefpiromeNoNo70minAbdominal distension
Tian Gao et al. [54]NANA16/MPsoriasis830i.v.gtt.①10% calcium gluconate injection, VCNoNo100mL remainedDizziness of unknown origin
Zhongli Zhang et al. [55]NANA4/FEmesis and hypogastralgia4NAi.v.gtt.②NANoNA30sAnaphylaxis
Zhongli Zhang et al. [55]NANA2/FFever of unknown origin4NAi.v.gtt.①NANoNA1minAnaphylaxis
Wei Zhu et al. [56]201210282013.3.2540/MUpper respiratory tract infections8NAi.v.gtt.②NANoNo150mL infusedAnaphylaxis
Wei Zhu et al. [56]201302022013.5.2510/FBronchial asthma2NAi.v.gtt.①NANoShrimp60mL infusedAnaphylaxis
Renze Yang et al. [57]070118NA6/MUpper respiratory tract infections2NAi.v.gtt.①AzithromycinNoNA4minAnaphylaxis
Renze Yang et al. [57]070118NA5/MUpper respiratory tract infections2NAi.v.gtt.①Ceftriaxone sodiumNoNA40mL infusedAnaphylaxis
Renze Yang et al. [57]070118NA9/MAmygdalitis2NAi.v.gtt.①Cefuroxime axetilNoNA10minAnaphylaxis
Renze Yang et al. [57]070118NA8/FBronchitis2NAi.v.gtt.①RoxithromycinNoNA3minAnaphylaxis
①5% glucose solution (5% GS); ②normal saline (N.S.); ③10% glucose solution (10% GS); ④5% glucose and sodium chloride injection.
NA: not available; i.v.gtt.: injectio venosa gutta; i.m.: intramuscular; VC: vitamin C injection.