Review Article

Normative Application of Xiyanping Injection: A Systematic Review of Adverse Case Reports

Table 6

Details of the symptoms of ADR cases.

SystemsSymptoms (occurrence number and percentage)

Skin structureCyanosis of lips (15, 6.7%); cyanosis (10, 4.4%); itch (10, 4.4%); rash (9, 4.0%); flush (6, 2.7%); maculopapule (4, 1.8%); urticaria (1, 0.5%); ecchymosis (1, 0.5%)
Systemic symptomsCold limbs (13, 5.8%); pallor (11, 4.9%); hyperhidrosis (9, 4.0%); Chills (8, 3.6%); feebleness (3, 1.3%); fever (1, 0.5%)
Digestive systemNausea (6, 2.7%); emesis (3, 1.3%); abdominal pain (2, 0.9%)
Respiratory systemDyspnea (13, 5.8%); short of breath (10, 4.4%); cough (4, 1.8%); polypnea (4, 1.8%); throat itching (1, 0.5%); nasal congestion (1, 0.5%)
Cardiovascular systemChest congestion (17, 7.6%); drop of blood pressure (15, 6.7%); tachycardia (12, 5.3%); palpitation (5, 2.2%); bradycardia (3, 1.3%)
Nervous systemIrritability (7, 3.1%); coma (4, 1.8%); tremor (4, 1.8%); confusion of consciousness (3, 1.3%); dizziness (3, 1.3%); numbness (2, 0.9%)
Urinary systemHydrocele (1, 0.5%); oliguria (1, 0.5%)
Application siteLocal swelling (2, 0.9%); headache (1, 0.5%)