A Network Pharmacology Approach to Uncover the Molecular Mechanisms of Herbal Formula Ban-Xia-Xie-Xin-Tang

Table 4

The general network properties of multilayer networks.

Level	Network parameter	BXXXT	Colitis	DM	GC
CN	Number of nodes	135	27	95	27
	Number of isolated nodes	49	22	55	13
	Average degree	4.13±5.75	0.3±0.67	0.86±1.52	1.63±2.1
	Average betweenness	32.9±71.86	0±0	8.16±26.43	2.48±5.92
	Density	0.0308	0.0114	0.0092	0.0627
	Cluster coefficient	0.2984	1.0000	0.2039	0.4225
	Diameter	6	1	7	4
	Shortest path	2.6333	1.0000	3.2270	2.0000
SPEN	Number of nodes	1083	174	722	160
	Number of isolated nodes	0	0	0	0
	Average degree	35.89±37.83	14.98±11.49	32.04±30.54	21.34±14.12
	Average betweenness	779.85±1964.53	117.51±173.57	523.02±1010.8	83.38±120.72
	Density	0.0332	0.0866	0.0444	0.1342
	Cluster coefficient	0.1642	0.2472	0.1975	0.2942
	Diameter	5	5	6	4
	Shortest path	2.4415	2.3584	2.4508	2.0487
NEN	Number of nodes	5374	1187	2439	2575
	Number of isolated nodes	0	0	0	0
	Average degree	46.56±73.94	40.49±51.12	43.67±57.71	44.77±63.8
	Average betweenness	4334.96±25925.21	830.27±3262.88	1923.32±6887.23	1813.74±13825.69
	Density	0.0087	0.0341	0.0179	0.0174
	Cluster coefficient	0.1006	0.1974	0.1494	0.1247
	Diameter	6	7	7	6
	Shortest path	2.6136	2.4001	2.5778	2.4093