<i>Wushenziye</i> Formula Inhibits Pancreatic <i>β</i> Cell Apoptosis in Type 2 Diabetes Mellitus via MEK-ERK-Caspase-3 Signaling Pathway

<div>Effects of WSZYF on the expressions of apoptosis-related proteins.<b> (a)</b> The relative expression of cleaved-caspase-3<i> in vivo</i>.<b> (b)</b> The relative expression of cleaved-caspase-3<i> in vitro</i>.<b> (c)</b> The ratio between p-ERK1/2 and ERK1/2<i> in vitro</i>.<b> (d)</b> The ratio between p-MEK1/2 and MEK1/2<i> in vitro</i>. <span class="nowrap"><svg height="10.7395pt" id="M9" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -10.1025 53.0975 10.7395" width="53.0975pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,2.179,-5.741)"><path d="M486 158C486 177 478 202 466 220C413 228 386 236 336 262C386 288 413 297 466 304C478 323 486 347 485 366C470 376 444 381 422 380C389 338 368 319 321 288C323 345 329 372 349 422C339 442 322 461 305 470C289 461 271 442 262 422C281 372 287 345 290 288C243 319 222 338 189 380C167 381 142 376 125 366C125 347 133 322 145 304C198 296 225 288 275 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Evidence-Based Complementary and Alternative Medicine

fig7

Figure 7

Figure 7: <i>Wushenziye</i> Formula Inhibits Pancreatic <i>β</i> Cell Apoptosis in Type 2 Diabetes Mellitus via MEK-ERK-Caspase-3 Signaling Pathway 

Evidence-Based Complementary and Alternative Medicine

Wushenziye Formula Inhibits Pancreatic β Cell Apoptosis in Type 2 Diabetes Mellitus via MEK-ERK-Caspase-3 Signaling Pathway

Figure 7