Grain Amaranth Is Associated with Improved Hepatic and Renal Calcium Metabolism in Type 2 Diabetes Mellitus of Male Wistar Rats

Figure 5

Structural changes in hepatic tissue after grain amaranth supplementation in male diabetic Wistar rats. KEY: Image A: T2DM + Mixtard®, B: positive control; D: T2DM + 50% AG; E: normal + 50% AG; F: negative control. N: nuclei of hepatocyte, Bvs: blood vessel, V: vacuolation, CV: central vein, black arrows: endothelium of blood vessel, Nec: necrosis. Mild vacuolation seen in T2DM and AG supplementation groups, but severe vacuolation and necrosis in T2DM without treatment. No changes in normal group.