Zuo Jin Wan Reverses DDP Resistance in Gastric Cancer through ROCK/PTEN/PI3K Signaling Pathway

Figure 5

ZJW inhibits tumor growth and induces apoptosis in SCG-7901/DDP xenografts animal model. Xenograft mice were divided into six groups: negative control (NC), DDP, ZJW, DDP combined with 500 mg/kg ZJW, DDP combined with 1000 mg/kg ZJW, and DDP combined with 2000 mg/kg ZJW. After 30-time treatment the nude mice were killed and tumor tissues were excised and weighed. (a) Representative tumor tissues isolated from each treatment group. (b) The weight of the dissected tumors from each treatment group. Mean ± SE, n = 6. P < 0.05, P < 0.01.

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