Research Article

A Double-Blind, Randomized, Crossover Comparative Study for Evaluating the Clinical Safety of Ephedrine Alkaloids-Free Ephedra Herb Extract (EFE)

Figure 1

Clinical trial flowchart. Single-institutional, double-blinded, randomized, two-drug, two-stage, and comparative crossover study design and implementation (enrollment, allocation, follow-up, and data analysis of the subjects administered EHE and EFE in two stages). EHE-P: prior administration of EHE; EFE-P: prior administration of EFE group.