A Double-Blind, Randomized, Crossover Comparative Study for Evaluating the Clinical Safety of Ephedrine Alkaloids-Free Ephedra Herb Extract (EFE)

Table 3

Comparison of various adverse events during EFE and EHE administration. p value derived from Fisher’s exact test.

	Incidence of Adverse Events			Odds ratio (confidence interval) of incidence during EFE administration/during EHE administration
	During EFE administration	During EHE administration	p value
Increased pulse rate	1 case/12 cases	4 cases/12 cases	0.32	0.18 (0.01-1.52)
Insomnia	1 case/12 cases	3 cases/12 cases	0.59	0.27 (0.01-2.56)
Hot flash	1 case/12 cases	0 cases/12 cases	1.00	not applicable
Dysuria	0 cases/12 cases	1 case/12 cases	1.00	not applicable