Investigation of Lake Hévíz Mineral Water Balneotherapy and Hévíz Mud Treatment in Murine Osteoarthritis and Rheumatoid Arthritis Models

Figure 3

Effects of balneotherapy on knee diameter in MIA-induced osteoarthritis model. Data points represent the percentage changes of the knee diameter throughout the 3-week experimental periods in mice treated with Hévíz water (a), Hévíz mud (b), and combined therapy with Hévíz water and mud (c) (30 mins on every weekday by the end of the study). Data are shown as means+SEM of n = 6– 8 mice/ group; p < 0.05, p < 0.01 versus respective controls; two-way ANOVA followed by Bonferroni’s multiple comparison test.

(a)

(b)

(c)